Which government agency is responsible for the issuance of driver's licenses in the country?

The Land Transportation Office (LTO) is the government agency specifically tasked with the issuance of driver's licenses in the country. This agency is responsible for regulating and overseeing all aspects related to land transportation, which includes not only the issuance of driver's licenses but also vehicle registration, conducting driving tests, and implementing policies related to road safety.

The Professional Regulation Commission focuses on the licensing and regulation of professionals in various fields, such as engineering, nursing, and teaching, and does not handle driver's licenses. The Department of Transportation oversees the overall transportation policy and may implement broader regulations, but it is not involved directly in issuing driver's licenses. Similarly, the Land Transportation Franchising and Regulatory Board primarily handles the regulation of public transport services, including the issuance of franchises and permits for public utilities. Thus, the LTO is the only agency among the options provided that directly issues driver's licenses.